Proteins are the building blocks of life and play a crucial role in all biological processes. Despite their importance, our understanding of how proteins work has been limited, which has hindered our ability to harness their full potential. However, recent advancements in protein design have allowed scientists to create new proteins with tailored functions, which opens up exciting possibilities for drug development, biotechnology, and beyond. This breakthrough is made possible by years of basic research, deep learning methods, directed evolution, the development of inexpensive computing, and the ability to read and write DNA.